P-474 Association between subchorionic hematoma’s size and miscarriage rate in IVF/ICSI patients

Abstract Study question What is the risk factor for miscarriage in patients undergoing IVF/ICSI with subchorionic hematoma(SCH) first trimester? Summary answer The size of SCH a IVF/ICSI. Miscarriage rate increases as grows. known already frequently observed pathology during routine ultrasound examinations early pregnancy. Its clinical significance has been unclear. Some studies believed that found trimester was not correlated adverse pregnancy outcome; Other can cause significant increase incidence late complications, such preterm labor, preeclampsia, and postpartum hemorrhage. Besides, what are factors pregnant women SCH? Answers to these questions urgently needed. design, size, duration Retrospective cohort study 646 at tertiary care university hospital, between February 2017 November 2020. Participants/materials, setting, methods All who underwent from 2020, achieved transvaginal our center were included. Risk explored. rates different sizes which expressed its' ratio area gestational sac compared. Main results role chance Patients had more embryos transferred (P=0.01), earlier detection IUH (P=0.003), smaller GS (P=0.03) prone miscarry. (P = 0.016). increased increasing trend: 0.003). Limitations, reasons caution main limitation this its retrospective nature relatively small sample size. Wider implications findings Extra attention needs be paid large SCH. There urgent need future research on affecting outcome underlying pathophysiological mechanisms. Trial registration number Not applicable